CDK14 a protein kinase of the CDK family. May play a role in meiosis as well as in neuron differentiation and/or function. Highly expressed in brain, pancreas, kidney, heart, testis and ovary. Two alternatively spliced isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: CDK family; CDK/TAIRE subfamily; CMGC group; Cell cycle regulation; EC; Kinase, protein; Motility/polarity/chemotaxis; Protein kinase, CMGC; Protein kinase, Ser/Thr (non-receptor); TAIRE subfamily
Chromosomal Location of Human Ortholog: 7q21.13
Cellular Component:  cytoplasmic cyclin-dependent protein kinase holoenzyme complex; cytosol; nucleus; plasma membrane
Molecular Function:  ATP binding; cyclin binding; cyclin-dependent protein serine/threonine kinase activity; protein binding
Biological Process:  cell division; G2/M transition of mitotic cell cycle; regulation of canonical Wnt signaling pathway; regulation of cell cycle; Wnt signaling pathway
Reference #:  O94921 (UniProtKB)
Alt. Names/Synonyms: CDK14; Cell division protein kinase 14; Cyclin-dependent kinase 14; hPFTAIRE1; KIAA0834; PFTAIRE protein kinase 1; PFTAIRE1; PFTK1; Serine/threonine-protein kinase PFTAIRE-1
Gene Symbols: CDK14
Molecular weight: 53,057 Da
Basal Isoelectric point: 9.06  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  KinBase  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene