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CDK17
May play a role in terminally differentiated neurons. Has a Ser/Thr-phosphorylating activity for histone H1. Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: CDK family; CDK/PCTAIRE subfamily; CMGC group; Cell cycle regulation; EC 2.7.11.22; Kinase, protein; Motility/polarity/chemotaxis; PCTAIRE subfamily; Protein kinase, CMGC; Protein kinase, Ser/Thr (non-receptor) |
| Chromosomal Location of human Ortholog: 12q23.1 |
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Cellular Component:
cytoplasm; nucleus
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Molecular Function:
ATP binding; cyclin-dependent protein serine/threonine kinase activity; protein binding; protein kinase activity; protein serine kinase activity
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Biological Process:
protein phosphorylation; regulation of cell cycle; regulation of transcription involved in G1/S transition of mitotic cell cycle
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Reference #:
Q00537
(UniProtKB)
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Alt. Names/Synonyms: CDK17; Cell division protein kinase 17; cyclin dependent kinase 17; Cyclin-dependent kinase 17; PCTAIRE-motif protein kinase 2; PCTAIRE2; PCTK2; protein kinase cdc2-related PCTAIRE-2; Serine/threonine-protein kinase PCTAIRE-2
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Gene Symbols: CDK17
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Molecular weight:
59,582 Da
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Basal Isoelectric point:
9.1
Predict pI for various phosphorylation states
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