NEK6 a protein kinase of the NEK family. Important in mitosis. May regulate spindle function. Note: This description may include information from UniProtKB.
Protein type: EC; Kinase, protein; NEK family; Other group; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 9q33.3
Cellular Component:  cytoplasm; cytosol; intracellular membrane-bounded organelle; microtubule; microtubule organizing center; nuclear speck; nucleoplasm; nucleus; protein-containing complex; spindle pole
Molecular Function:  activating transcription factor binding; ATP binding; kinesin binding; magnesium ion binding; protein binding; protein kinase binding; protein serine/threonine kinase activity; transcription corepressor binding; ubiquitin protein ligase binding
Biological Process:  apoptotic process; cell division; chromosome segregation; mitotic nuclear envelope disassembly; peptidyl-serine phosphorylation; protein autophosphorylation; protein phosphorylation; regulation of cellular senescence; regulation of mitotic cell cycle; regulation of mitotic metaphase/anaphase transition; spindle assembly
Reference #:  Q9HC98 (UniProtKB)
Alt. Names/Synonyms: NEK6; Never in mitosis A-related kinase 6; NIMA (never in mitosis gene a)-related kinase 6; NimA-related protein kinase 6; Protein kinase SID6-1512; putative serine-threonine protein kinase; Serine/threonine-protein kinase Nek6; SID6-1512
Gene Symbols: NEK6
Molecular weight: 35,714 Da
Basal Isoelectric point: 8.26  Predict pI for various phosphorylation states
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