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SNAP23
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion. Belongs to the SNAP-25 family. Ubiquitous. Highest levels where found in placenta. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Vesicle |
| Chromosomal Location of human Ortholog: 15q15.1-q15.2 |
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Cellular Component:
adherens junction; azurophil granule; cytoplasm; mitochondrion; neuron projection; nucleoplasm; phagocytic vesicle membrane; plasma membrane; presynapse; SNARE complex; specific granule; specific granule membrane; synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex; tertiary granule membrane
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Molecular Function:
protein binding; SNAP receptor activity; syntaxin binding; syntaxin-1 binding
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Biological Process:
exocytosis; histamine secretion by mast cell; membrane fusion; post-Golgi vesicle-mediated transport; protein transport; synaptic vesicle fusion to presynaptic active zone membrane; synaptic vesicle priming; vesicle targeting
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Reference #:
O00161
(UniProtKB)
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Alt. Names/Synonyms: HsT17016; SNAP-23; SNAP23; SNAP23A; SNAP23B; SNP23; Synaptosomal-associated protein 23; synaptosomal-associated protein, 23kD; synaptosomal-associated protein, 23kDa; synaptosome associated protein 23; synaptosome associated protein 23kDa; Vesicle-membrane fusion protein SNAP-23
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Gene Symbols: SNAP23
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Molecular weight:
23,354 Da
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Basal Isoelectric point:
4.89
Predict pI for various phosphorylation states
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