SNAP23 Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion. Belongs to the SNAP-25 family. Ubiquitous. Highest levels where found in placenta. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Vesicle
Chromosomal Location of human Ortholog: 15q15.1-q15.2
Cellular Component:  azurophil granule; cell-cell adherens junction; cytoplasm; mast cell granule; neuron projection; nucleoplasm; phagocytic vesicle membrane; plasma membrane; presynapse; SNARE complex; specific granule; specific granule membrane; tertiary granule membrane
Molecular Function:  protein binding; syntaxin binding
Biological Process:  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; histamine secretion by mast cell; membrane fusion; neutrophil degranulation; post-Golgi vesicle-mediated transport; protein transport; vesicle targeting
Reference #:  O00161 (UniProtKB)
Alt. Names/Synonyms: HsT17016; SNAP-23; SNAP23; SNAP23A; SNAP23B; SNP23; Synaptosomal-associated protein 23; synaptosomal-associated protein, 23kD; synaptosomal-associated protein, 23kDa; synaptosome associated protein 23; synaptosome associated protein 23kDa; Vesicle-membrane fusion protein SNAP-23
Gene Symbols: SNAP23
Molecular weight: 23,354 Da
Basal Isoelectric point: 4.89  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein