VAMP3 SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network. Belongs to the synaptobrevin family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral
Chromosomal Location of human Ortholog: 1p36.23
Cellular Component:  cell surface; clathrin-coated endocytic vesicle membrane; clathrin-coated vesicle; cytosol; early endosome membrane; intracellular membrane-bounded organelle; membrane; neuron projection; perinuclear region of cytoplasm; phagocytic vesicle membrane; plasma membrane; recycling endosome; recycling endosome membrane; secretory granule; SNARE complex; synapse; trans-Golgi network membrane; transport vesicle
Molecular Function:  protein binding; SNAP receptor activity; syntaxin-1 binding
Biological Process:  calcium-ion regulated exocytosis; cellular response to type II interferon; exocytosis; Golgi to plasma membrane protein transport; membrane fusion; mucus secretion; negative regulation of secretion by cell; positive regulation of immunoglobulin production; positive regulation of receptor recycling; protein-containing complex assembly; regulation of histamine secretion by mast cell; retrograde transport, endosome to Golgi; SNARE complex assembly; substrate adhesion-dependent cell spreading; vesicle docking involved in exocytosis; vesicle fusion; vesicle-mediated transport
Reference #:  Q15836 (UniProtKB)
Alt. Names/Synonyms: CEB; Cellubrevin; SYB3; Synaptobrevin-3; VAMP-3; VAMP3; vesicle associated membrane protein 3; Vesicle-associated membrane protein 3; vesicle-associated membrane protein 3 (cellubrevin)
Gene Symbols: VAMP3
Molecular weight: 11,309 Da
Basal Isoelectric point: 8.89  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein