VAMP1 Involved in the targeting and/or fusion of transport vesicles to their target membrane. Belongs to the synaptobrevin family. Nervous system, skeletal muscle and adipose tissue. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 12p13.31
Cellular Component:  cell junction; cell surface; cytosol; glutamatergic synapse; integral component of plasma membrane; integral component of synaptic vesicle membrane; mitochondrial outer membrane; neuromuscular junction; neuron projection; specific granule membrane; synaptic vesicle membrane; tertiary granule membrane
Molecular Function:  protein binding
Biological Process:  regulation of synaptic vesicle fusion to presynaptic active zone membrane; SNARE complex assembly; synaptic vesicle priming
Disease: Myasthenic Syndrome, Congenital, 25, Presynaptic; Spastic Ataxia 1, Autosomal Dominant
Reference #:  P23763 (UniProtKB)
Alt. Names/Synonyms: CMS25; DKFZp686H12131; SPAX1; SYB1; synaptobrevin 1; Synaptobrevin-1; VAMP-1; VAMP1; vesicle associated membrane protein 1; Vesicle-associated membrane protein 1; vesicle-associated membrane protein 1 (synaptobrevin 1)
Gene Symbols: VAMP1
Molecular weight: 12,902 Da
Basal Isoelectric point: 6.24  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein