NPY1R Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY Belongs to the G-protein coupled receptor 1 family. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of mouse Ortholog: 8 B3.1|8 33.15 cM
Cellular Component:  axon; glutamatergic synapse; membrane; neuron projection; neuronal dense core vesicle; plasma membrane; presynaptic membrane; synaptic vesicle
Molecular Function:  G protein-coupled receptor activity; neuropeptide binding; neuropeptide receptor activity; neuropeptide Y receptor activity; pancreatic polypeptide receptor activity; peptide YY receptor activity
Biological Process:  feeding behavior; G protein-coupled receptor signaling pathway; glucose metabolic process; locomotory behavior; negative regulation of cytosolic calcium ion concentration; negative regulation of hormone secretion; outflow tract morphogenesis; peristalsis; positive regulation of vasoconstriction; regulation of blood pressure; regulation of multicellular organism growth; regulation of presynaptic cytosolic calcium ion concentration; regulation of synaptic vesicle exocytosis; sensory perception of pain; signal transduction; synaptic signaling via neuropeptide
Reference #:  Q04573 (UniProtKB)
Alt. Names/Synonyms: neuropeptide Y receptor subtype; Neuropeptide Y receptor type 1; neuropeptide Y receptor Y1; NPY-1 receptor; NPY1-R; Npy1r; Npyr; Y1-; Y1-R
Gene Symbols: Npy1r
Molecular weight: 44,015 Da
Basal Isoelectric point: 8.53  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene