GPRC5C This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways. Belongs to the G-protein coupled receptor 3 family. Expression is highest in the periphery, particularly in the stomach, but also in the kidney, liver, pancreas, and prostate. In brain, levels of expression are generally lower than in the periphery, with the exception of cerebellum, spinal cord, and dorsal root ganglia (DRG). 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 3; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of human Ortholog: 17q25.1
Cellular Component:  cytoplasmic vesicle membrane; extracellular exosome; intracellular membrane-bounded organelle; plasma membrane; receptor complex
Molecular Function:  G protein-coupled receptor activity; protein kinase activator activity
Biological Process:  G protein-coupled receptor signaling pathway
Reference #:  Q9NQ84 (UniProtKB)
Alt. Names/Synonyms: G protein-coupled receptor class C group 5 member C; G protein-coupled receptor, family C, group 5, member C; G-protein coupled receptor family C group 5 member C; GPC5C; GPRC5C; MGC131820; orphan G-protein coupled receptor; RAIG-3; RAIG3; retinoic acid responsive gene protein; Retinoic acid-induced gene 3 protein
Gene Symbols: GPRC5C
Molecular weight: 48,193 Da
Basal Isoelectric point: 8.72  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene