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GPRC5C
This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways. Belongs to the G-protein coupled receptor 3 family. Expression is highest in the periphery, particularly in the stomach, but also in the kidney, liver, pancreas, and prostate. In brain, levels of expression are generally lower than in the periphery, with the exception of cerebellum, spinal cord, and dorsal root ganglia (DRG). 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: GPCR, family 3; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR |
| Chromosomal Location of human Ortholog: 17q25.1 |
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Cellular Component:
cytoplasmic vesicle membrane; extracellular exosome; intracellular membrane-bounded organelle; plasma membrane; receptor complex
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Molecular Function:
G protein-coupled receptor activity; protein kinase activator activity
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Biological Process:
activation of protein kinase activity; G protein-coupled receptor signaling pathway
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Reference #:
Q9NQ84
(UniProtKB)
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Alt. Names/Synonyms: G protein-coupled receptor class C group 5 member C; G protein-coupled receptor, family C, group 5, member C; G-protein coupled receptor family C group 5 member C; GPC5C; GPRC5C; MGC131820; orphan G-protein coupled receptor; RAIG-3; RAIG3; retinoic acid responsive gene protein; Retinoic acid-induced gene 3 protein
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Gene Symbols: GPRC5C
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Molecular weight:
48,193 Da
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Basal Isoelectric point:
8.72
Predict pI for various phosphorylation states
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