CNP May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. Belongs to the 2H phosphoesterase superfamily. CNPase family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cell development/differentiation; EC 3.1.4.37; Phosphodiesterase
Chromosomal Location of Human Ortholog: 11 D|11 63.47 cM
Cellular Component:  cell projection; cytoplasm; cytosol; extracellular space; membrane; microtubule; microvillus; mitochondrial inner membrane; mitochondrial outer membrane; myelin sheath; myelin sheath abaxonal region; myelin sheath adaxonal region; nucleoplasm; nucleus; perinuclear region of cytoplasm; plasma membrane; pseudopodium
Molecular Function:  2',3'-cyclic-nucleotide 3'-phosphodiesterase activity; cyclic nucleotide binding; hydrolase activity; RNA binding
Biological Process:  adult locomotory behavior; axonogenesis; cyclic nucleotide catabolic process; microtubule cytoskeleton organization; oligodendrocyte differentiation; regulation of mitochondrial membrane permeability; response to toxic substance
Reference #:  P16330 (UniProtKB)
Alt. Names/Synonyms: 2',3'-cyclic nucleotide 3' phosphodiesterase; 2',3'-cyclic-nucleotide 3'-phosphodiesterase; CN37; CNP; Cnp-1; Cnp1; CNPase; cyclic nucleotide phosphodiesterase 1; OTTMUSP00000001946
Gene Symbols: Cnp
Molecular weight: 47,123 Da
Basal Isoelectric point: 9.08  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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CNP

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene