CNP May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. Belongs to the 2H phosphoesterase superfamily. CNPase family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cell development/differentiation; EC 3.1.4.37; Phosphodiesterase
Chromosomal Location of Human Ortholog: 17q21.2
Cellular Component:  cytoplasm; cytosol; extracellular space; melanosome; microvillus; mitochondrial inner membrane; mitochondrial outer membrane; myelin sheath abaxonal region; myelin sheath adaxonal region; nucleoplasm; nucleus; perinuclear region of cytoplasm; plasma membrane; pseudopodium
Molecular Function:  cyclic nucleotide binding; RNA binding
Biological Process:  adult locomotory behavior; aging; axonogenesis; chemical synaptic transmission; cyclic nucleotide catabolic process; forebrain development; microtubule cytoskeleton organization; oligodendrocyte differentiation; regulation of mitochondrial membrane permeability; response to lipopolysaccharide; response to toxic substance
Disease: Leukodystrophy, Hypomyelinating, 20
Reference #:  P09543 (UniProtKB)
Alt. Names/Synonyms: 2', 3' cyclic nucleotide 3' phosphohydrolase; 2',3'-cyclic nucleotide 3' phosphodiesterase; 2',3'-cyclic-nucleotide 3'-phosphodiesterase; CN37; CNP; CNP1; CNPase
Gene Symbols: CNP
Molecular weight: 47,579 Da
Basal Isoelectric point: 9.17  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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CNP

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene