RAB34 Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes. Acts also as a positive regulator of hedgehog signaling and regulates ciliary function. Belongs to the small GTPase superfamily. Rab family. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: G protein, monomeric; G protein, monomeric, Rab; Nucleolus
Chromosomal Location of Human Ortholog: 17q11.2
Cellular Component:  cilium; Golgi apparatus; Golgi cisterna; Golgi stack; perinuclear region of cytoplasm; phagocytic vesicle; phagocytic vesicle membrane; vesicle
Molecular Function:  GTP binding; GTP-dependent protein binding; protein binding; Ral GTPase binding
Biological Process:  antigen processing and presentation; cell projection organization; Golgi to plasma membrane protein transport; lysosome localization; phagosome maturation; phagosome-lysosome fusion; positive regulation of smoothened signaling pathway; protein localization to plasma membrane
Reference #:  Q9BZG1 (UniProtKB)
Alt. Names/Synonyms: NARR; RAB34; RAB34, member RAS oncogene family; RAB39; RAH; Ras-related protein Rab-34; Ras-related protein Rab-39; Ras-related protein Rah
Gene Symbols: RAB34
Molecular weight: 29,044 Da
Basal Isoelectric point: 8.07  Predict pI for various phosphorylation states
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RAB34

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein