ZDHHC7 Palmitoyltransferase with broad specificity. Palmitoylates JAM3. Palmitoylates SNAP25 and DLG4/PSD95. Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane and their function in rapid intracellular signaling upon binding of sex hormones. May play a role in follicle stimulation hormone (FSH) activation of testicular Sertoli cells. Belongs to the DHHC palmitoyltransferase family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC; Membrane protein, integral; Membrane protein, multi-pass; Palmitoyltransferase; Transferase
Chromosomal Location of human Ortholog: 16q24.1
Cellular Component:  Golgi apparatus; Golgi membrane; integral component of membrane
Molecular Function:  palmitoyltransferase activity; protein-cysteine S-palmitoyltransferase activity
Biological Process:  peptidyl-L-cysteine S-palmitoylation; protein palmitoylation
Reference #:  Q9NXF8 (UniProtKB)
Alt. Names/Synonyms: Acyltransferase ZDHHC7; DHHC-7; DHHC7; FLJ10792; FLJ20279; Palmitoyltransferase ZDHHC7; Sertoli cell gene with zinc finger domain-β Sertoli cell gene with zinc finger domain-beta; Sertoli cell gene with zinc finger domain-I(2); SERZ-B; SERZ1; ZDHC7; ZDHHC7; Zinc finger DHHC domain-containing protein 7; zinc finger DHHC-type containing 7; zinc finger DHHC-type palmitoyltransferase 7; Zinc finger protein 370; zinc finger, DHHC domain containing 7; zinc finger, DHHC-type containing 7; ZNF370
Gene Symbols: ZDHHC7
Molecular weight: 35,140 Da
Basal Isoelectric point: 8.28  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein