NPY1R
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY Belongs to the G-protein coupled receptor 1 family. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of human Ortholog: 4q32.2
Cellular Component:
neuron projection; plasma membrane
Molecular Function:
neuropeptide binding; neuropeptide receptor activity; neuropeptide Y receptor activity; pancreatic polypeptide receptor activity; peptide YY receptor activity; protein binding
Biological Process:
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; feeding behavior; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; glucose metabolic process; locomotory behavior; neuropeptide signaling pathway; outflow tract morphogenesis; regulation of blood pressure; regulation of multicellular organism growth; sensory perception of pain
Reference #:
P25929
(UniProtKB)
Alt. Names/Synonyms: Neuropeptide Y receptor type 1; neuropeptide Y receptor Y1; NPY1-R; NPY1R; NPYR; NPYY1
Gene Symbols: NPY1R
Molecular weight:
44,392 Da
Basal Isoelectric point:
7.94
Predict pI for various phosphorylation states
Select Structure to View Below
NPY1R
2F1U - A=38-67, B=74-103, C=110-142, D=153-175, E=208-233, F=258-288, G=300-320 (human)
2IIL - @=1-384 (human)
5ZBH - A=250-358 (human)
5ZBQ - A=2-358 (human)
7VGX - L=29-64 (human)
7X9A - P=29-64 (human)
8K6M - E=29-64 (human)
8K6O - E=29-64 (human)