NPY1R Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY Belongs to the G-protein coupled receptor 1 family. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of human Ortholog: 4q32.2
Cellular Component:  neuron projection; plasma membrane
Molecular Function:  neuropeptide binding; neuropeptide receptor activity; neuropeptide Y receptor activity; pancreatic polypeptide receptor activity; peptide YY receptor activity; protein binding
Biological Process:  adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; feeding behavior; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; glucose metabolic process; locomotory behavior; neuropeptide signaling pathway; outflow tract morphogenesis; regulation of blood pressure; regulation of multicellular organism growth; sensory perception of pain
Reference #:  P25929 (UniProtKB)
Alt. Names/Synonyms: Neuropeptide Y receptor type 1; neuropeptide Y receptor Y1; NPY1-R; NPY1R; NPYR; NPYY1
Gene Symbols: NPY1R
Molecular weight: 44,392 Da
Basal Isoelectric point: 7.94  Predict pI for various phosphorylation states
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NPY1R

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene