PLBD1 In view of the small size of the putative binding pocket, it has been proposed that it may act as an amidase or a peptidase. Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids. Belongs to the phospholipase B-like family. Expressed in neutrophils and monocytes. Note: This description may include information from UniProtKB.
Protein type: EC 3.1.1.-; Hydrolase; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 12p13.1
Cellular Component:  cytosol; extracellular space; lysosome
Molecular Function:  hydrolase activity
Biological Process:  lipid catabolic process; phosphatidylcholine acyl-chain remodeling; phosphatidylethanolamine acyl-chain remodeling; phosphatidylinositol acyl-chain remodeling; phospholipid metabolic process
Reference #:  Q6P4A8 (UniProtKB)
Alt. Names/Synonyms: FLJ22662; LAMA-like protein 1; Lamina ancestor homolog 1; phospholipase B domain containing 1; Phospholipase B domain-containing protein 1; Phospholipase B-like 1; PLB homolog 1; PLBD1; PLBL1; Putative phospholipase B-like 1
Gene Symbols: PLBD1
Molecular weight: 63,255 Da
Basal Isoelectric point: 9.11  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB