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PLBD1
In view of the small size of the putative binding pocket, it has been proposed that it may act as an amidase or a peptidase. Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids. Belongs to the phospholipase B-like family. Expressed in neutrophils and monocytes. Note: This description may include information from UniProtKB.
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| Protein type: EC 3.1.1.-; Hydrolase; Secreted; Secreted, signal peptide |
| Chromosomal Location of human Ortholog: 12p13.1 |
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Cellular Component:
cytosol; extracellular region; extracellular space; lysosome
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Molecular Function:
phospholipase activity
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Biological Process:
phospholipid catabolic process
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Reference #:
Q6P4A8
(UniProtKB)
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Alt. Names/Synonyms: FLJ22662; LAMA-like protein 1; Lamina ancestor homolog 1; phospholipase B domain containing 1; Phospholipase B domain-containing protein 1; Phospholipase B-like 1; Phospholipase B-like 1 chain A; Phospholipase B-like 1 chain B; Phospholipase B-like 1 chain C; PLB homolog 1; PLBD1; PLBL1; Putative phospholipase B-like 1
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Gene Symbols: PLBD1
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Molecular weight:
63,255 Da
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Basal Isoelectric point:
9.11
Predict pI for various phosphorylation states
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