FAM83H May play a major role in the structural organization and calcification of developing enamel. May play a role in keratin cytoskeleton disassembly by recruiting CSNK1A1 to keratin filaments. Thereby, it may regulate epithelial cell migration. Belongs to the FAM83 family. Expressed in the tooth follicle. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of human Ortholog: 8q24.3
Cellular Component:  cytoplasm; keratin filament
Molecular Function:  keratin filament binding; protein binding; protein kinase binding
Biological Process:  biomineral tissue development; intermediate filament cytoskeleton organization; positive regulation of cell migration; protein localization to cytoskeleton; signal transduction
Disease: Amelogenesis Imperfecta, Type Iii
Reference #:  Q6ZRV2 (UniProtKB)
Alt. Names/Synonyms: AI3; AI3A; FA83H; FAM83H; FAM83H variant 1; FAM83H variant 2; family with sequence similarity 83 member H; family with sequence similarity 83, member H; FLJ46072; Protein FAM83H; truncated FAM83H
Gene Symbols: FAM83H
Molecular weight: 127,122 Da
Basal Isoelectric point: 6.52  Predict pI for various phosphorylation states
Select Structure to View Below

FAM83H

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein