SLC6A12 Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A12 subfamily. Liver, heart, skeletal muscle, placenta, and a widespread distribution in the brain. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family
Cellular Component:  integral component of plasma membrane
Biological Process:  gamma-aminobutyric acid transport; transmembrane transport
Reference #:  P27799 (UniProtKB)
Alt. Names/Synonyms: Na /Cl- betaine/GABA transporter; S6A12; S6AC; SLC6A12; Sodium- and chloride-dependent betaine transporter; solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
Gene Symbols: SLC6A12
Molecular weight: 69,292 Da
Basal Isoelectric point: 5.67  Predict pI for various phosphorylation states
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SLC6A12

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene