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TREML1
Cell surface receptor that may play a role in the innate and adaptive immune response. Detected in platelets, monocytic leukemia and in T-cell leukemia. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Immunoglobulin superfamily; Membrane protein, integral |
| Chromosomal Location of human Ortholog: 6p21.1 |
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Cellular Component:
cell surface; cytosol; Golgi apparatus; membrane; nuclear speck; plasma membrane; platelet alpha granule
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Molecular Function:
protein binding; transmembrane signaling receptor activity
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Biological Process:
innate immune response; platelet activation
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Reference #:
Q86YW5
(UniProtKB)
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Alt. Names/Synonyms: dJ238O23.3; GLTL1825; MGC119173; PRO3438; TLT-1; TLT1; Trem-like transcript 1 protein; TREML1; triggering receptor expressed on myeloid cells like 1; triggering receptor expressed on myeloid cells-like 1; Triggering receptor expressed on myeloid cells-like protein 1; TRML1
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Gene Symbols: TREML1
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Molecular weight:
32,679 Da
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Basal Isoelectric point:
5.7
Predict pI for various phosphorylation states
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