RAB6B Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells. Belongs to the small GTPase superfamily. Rab family. Predominantly expressed in brain. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: G protein; G protein, monomeric; G protein, monomeric, Rab
Chromosomal Location of human Ortholog: 3q22.1
Cellular Component:  cytoplasmic vesicle; cytosol; endoplasmic reticulum-Golgi intermediate compartment; Golgi apparatus; Golgi membrane; presynapse
Molecular Function:  GTP binding; GTPase activity; myosin V binding; protein binding
Biological Process:  retrograde vesicle-mediated transport, Golgi to ER
Reference #:  Q9NRW1 (UniProtKB)
Alt. Names/Synonyms: RAB6B; RAB6B, member RAS oncogene family; Ras-related protein Rab-6B; small GTP-binding protein; small GTPase RAB6B
Gene Symbols: RAB6B
Molecular weight: 23,462 Da
Basal Isoelectric point: 5.41  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene