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RAB6B
Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells. Belongs to the small GTPase superfamily. Rab family. Predominantly expressed in brain. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: G protein; G protein, monomeric; G protein, monomeric, Rab |
| Chromosomal Location of human Ortholog: 3q22.1 |
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Cellular Component:
cytoplasmic vesicle; cytosol; endomembrane system; endoplasmic reticulum-Golgi intermediate compartment; Golgi apparatus; Golgi membrane; presynapse
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Molecular Function:
GTP binding; GTPase activity; myosin V binding; protein binding
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Biological Process:
Golgi organization; intra-Golgi vesicle-mediated transport; intracellular protein transport; neuron projection development; protein localization to Golgi membrane; retrograde transport, endosome to Golgi; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
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Reference #:
Q9NRW1
(UniProtKB)
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Alt. Names/Synonyms: RAB6B; RAB6B, member RAS oncogene family; Ras-related protein Rab-6B; small GTP-binding protein; small GTPase RAB6B
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Gene Symbols: RAB6B
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Molecular weight:
23,462 Da
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Basal Isoelectric point:
5.41
Predict pI for various phosphorylation states
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