ANXA4 Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. Belongs to the annexin family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Calcium-binding; Lipid-binding
Chromosomal Location of mouse Ortholog: 6 D1|6 37.75 cM
Cellular Component:  apical plasma membrane; cell surface; cytoplasm; cytosol; nuclear membrane; nucleus; perinuclear region of cytoplasm; plasma membrane; vesicle membrane
Molecular Function:  calcium ion binding; calcium-dependent phospholipid binding; calcium-dependent protein binding; chondroitin sulfate binding; heparin binding; identical protein binding; NF-kappaB binding; protein binding
Biological Process:  epithelial cell differentiation; kidney development; negative regulation of interleukin-8 secretion; negative regulation of NF-kappaB transcription factor activity; Notch signaling pathway; regulation of transcription by RNA polymerase II
Reference #:  P97429 (UniProtKB)
Alt. Names/Synonyms: AI265406; AIV; Annexin A4; Annexin IV; Annexin-4; Anx4; Anxa4; AW106930; OTTMUSP00000024984; Xanx; Xanx-4
Gene Symbols: Anxa4
Molecular weight: 35,916 Da
Basal Isoelectric point: 5.43  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene