ABCB9 ATP-dependent low-affinity peptide transporter which translocates a broad spectrum of peptides from the cytosol to the lysosomal lumen. Displays a broad peptide length specificity from 6-mer up to at least 59-mer peptides with an optimum of 23-mers. Favors positively charged, aromatic or hydrophobic residues in the N- and C-terminal positions whereas negatively charged residues as well as asparagine and methionine are not favored. Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily. 5 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ABC family
Chromosomal Location of Human Ortholog: 5|5 F
Cellular Component:  endoplasmic reticulum membrane; integral component of endoplasmic reticulum membrane; integral component of membrane; intracellular membrane-bounded organelle; lysosomal membrane; lysosome; membrane
Molecular Function:  ATP binding; ATPase activity; ATPase activity, coupled to transmembrane movement of substances; nucleotide binding; peptide-transporting ATPase activity; protein homodimerization activity; transmembrane transporter activity
Biological Process:  peptide transport; protein transport; transmembrane transport
Reference #:  Q9JJ59 (UniProtKB)
Alt. Names/Synonyms: ABC transporter 9 protein; Abcb9; ATP-binding cassette sub-family B member 9; ATP-binding cassette transporter 9; ATP-binding cassette, sub-family B (MDR/TAP), member 9; ATP-binding cassette, sub-family B, member 9; Kiaa1520; mABCB9; mKIAA1520; TAP-like protein; TAPL
Gene Symbols: Abcb9
Molecular weight: 83,963 Da
Basal Isoelectric point: 7.3  Predict pI for various phosphorylation states
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ABCB9

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene