PAI-RBP1 a predicted RNA-binding protein. May specifically binds the mRNA of type-1 plasminogen activator inhibitor (PAI-1), and is thought to be involved in regulation of mRNA stability. A related rat protein RDA288 plays a significant role in mediating the anti-apoptotic action of progesterone in granulosa cells. Note: This description may include information from UniProtKB.
Protein type: RNA-binding
Chromosomal Location of Human Ortholog: 1p31.3
Cellular Component:  cytoplasm; cytosol; nucleus; perinuclear region of cytoplasm; plasma membrane
Molecular Function:  mRNA 3'-UTR binding; protein binding; SUMO binding
Biological Process:  PML body organization; regulation of apoptotic process; regulation of mRNA stability
Reference #:  Q8NC51 (UniProtKB)
Alt. Names/Synonyms: CGI-55; CHD3IP; chromodomain helicase DNA binding protein 3 interacting protein; DKFZp564M2423; FLJ90489; HABP4L; PAI-1 mRNA binding protein; PAI-RBP1; PAI1 RNA-binding protein 1; PAIRB; PAIRBP1; plasminogen activator inhibitor 1 RNA binding protein; Plasminogen activator inhibitor 1 RNA-binding protein; SERBP1; SERPINE1 mRNA binding protein 1; SERPINE1 mRNA-binding protein 1
Gene Symbols: SERBP1
Molecular weight: 44,965 Da
Basal Isoelectric point: 8.66  Predict pI for various phosphorylation states
Select Structure to View Below

PAI-RBP1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein