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FOXN3
Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints). 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: DNA-binding; Transcription factor |
| Chromosomal Location of human Ortholog: 14q31.3-q32.11 |
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Cellular Component:
chromatin; nucleus
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Molecular Function:
cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; protein binding
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Biological Process:
craniofacial suture morphogenesis; mitotic G2 DNA damage checkpoint signaling; negative regulation of DNA-templated transcription; regulation of DNA-templated transcription; regulation of transcription by RNA polymerase II
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Reference #:
O00409
(UniProtKB)
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Alt. Names/Synonyms: C14orf116; Checkpoint suppressor 1; CHES1; forkhead box N3; Forkhead box protein N3; FOXN3; PRO1635
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Gene Symbols: FOXN3
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Molecular weight:
53,835 Da
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Basal Isoelectric point:
6.19
Predict pI for various phosphorylation states
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