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SRp46
Involved in pre-mRNA alternative splicing. Belongs to the splicing factor SR family. Strongly expressed in pancreas, spleen and prostate. Weakly expressed in lung, liver and thymus. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: RNA-binding |
| Chromosomal Location of human Ortholog: 11q21 |
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Cellular Component:
cytosol; nuclear speck; nucleoplasm
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Molecular Function:
protein binding; RNA binding
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Biological Process:
mRNA splicing, via spliceosome
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Reference #:
Q9BRL6
(UniProtKB)
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Alt. Names/Synonyms: DSM-1; Pre-mRNA-splicing factor SRP46; serine and arginine rich splicing factor 8; Serine/arginine-rich splicing factor 8; SFR2B; SFRS2B; Splicing factor SRp46; Splicing factor, arginine/serine-rich 2B; splicing factor, arginine/serine-rich, 46kD; SR splicing factor 8; SRP46; SRSF8
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Gene Symbols: SRSF8
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Molecular weight:
32,288 Da
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Basal Isoelectric point:
11.72
Predict pI for various phosphorylation states
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