SRp46 Involved in pre-mRNA alternative splicing. Belongs to the splicing factor SR family. Strongly expressed in pancreas, spleen and prostate. Weakly expressed in lung, liver and thymus. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: RNA-binding
Chromosomal Location of human Ortholog: 11q21
Cellular Component:  cytosol; nuclear speck; nucleus
Molecular Function:  protein binding
Reference #:  Q9BRL6 (UniProtKB)
Alt. Names/Synonyms: DSM-1; Pre-mRNA-splicing factor SRP46; serine and arginine rich splicing factor 8; Serine/arginine-rich splicing factor 8; SFR2B; SFRS2B; Splicing factor SRp46; Splicing factor, arginine/serine-rich 2B; splicing factor, arginine/serine-rich, 46kD; SR splicing factor 8; SRP46; SRSF8
Gene Symbols: SRSF8
Molecular weight: 32,288 Da
Basal Isoelectric point: 11.72  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene