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NARG2
Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Belongs to the ICE2 family. Expressed at low levels in lung and testis. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Unknown function |
| Chromosomal Location of human Ortholog: 15q22.2 |
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Cellular Component:
Cajal body; cytosol; euchromatin; histone locus body; nuclear body; nucleoplasm; transcription elongation factor complex
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Molecular Function:
protein binding
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Biological Process:
positive regulation of transcription by RNA polymerase III; snRNA transcription by RNA polymerase II; snRNA transcription by RNA polymerase III
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Reference #:
Q659A1
(UniProtKB)
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Alt. Names/Synonyms: BRCC1; breast cancer cell 1; ICE2; interactor of little elongation complex ELL subunit 2; Interactor of little elongator complex ELL subunit 2; Little elongation complex subunit 2; NARG2; NMDA receptor regulated 2; NMDA receptor-regulated gene 2; NMDA receptor-regulated protein 2
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Gene Symbols: ICE2
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Molecular weight:
110,011 Da
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Basal Isoelectric point:
6.69
Predict pI for various phosphorylation states
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