CDKL1 Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. Highly expressed in kidney, and to a lower extent in ovary. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: CDKL family; CMGC group; Cell cycle regulation; EC 2.7.11.22; Kinase, protein; Protein kinase, CMGC; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of human Ortholog: 14q21.3
Cellular Component:  ciliary transition zone; cytoplasm; intracellular membrane-bounded organelle; nucleoplasm; nucleus
Molecular Function:  ATP binding; cyclin-dependent protein serine/threonine kinase activity; protein serine kinase activity
Biological Process:  protein phosphorylation; regulation of cell cycle; regulation of cilium assembly
Reference #:  Q00532 (UniProtKB)
Alt. Names/Synonyms: CDC2-related kinase 1; CDKL1; cyclin dependent kinase like 1; Cyclin-dependent kinase-like 1; cyclin-dependent kinase-like 1 (CDC2-related kinase); KKIALRE; P42; Protein kinase p42 KKIALRE; serine/threonine protein kinase KKIALRE; Serine/threonine-protein kinase KKIALRE
Gene Symbols: CDKL1
Molecular weight: 41,671 Da
Basal Isoelectric point: 9.04  Predict pI for various phosphorylation states
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CDKL1

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  KinBase  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB