CDKL1
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. Highly expressed in kidney, and to a lower extent in ovary. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
|
Protein type: CDKL family; CMGC group; Cell cycle regulation; EC 2.7.11.22; Kinase, protein; Protein kinase, CMGC; Protein kinase, Ser/Thr (non-receptor) |
Chromosomal Location of human Ortholog: 14q21.3 |
Cellular Component:
ciliary transition zone; cytoplasm; intracellular membrane-bounded organelle; nucleoplasm; nucleus
|
Molecular Function:
ATP binding; cyclin-dependent protein serine/threonine kinase activity; protein serine kinase activity
|
Biological Process:
protein phosphorylation; regulation of cell cycle; regulation of cilium assembly
|
Reference #:
Q00532
(UniProtKB)
|
Alt. Names/Synonyms: CDC2-related kinase 1; CDKL1; cyclin dependent kinase like 1; Cyclin-dependent kinase-like 1; cyclin-dependent kinase-like 1 (CDC2-related kinase); KKIALRE; P42; Protein kinase p42 KKIALRE; serine/threonine protein kinase KKIALRE; Serine/threonine-protein kinase KKIALRE
|
Gene Symbols: CDKL1
|
Molecular weight:
41,671 Da
|
Basal Isoelectric point:
9.04
Predict pI for various phosphorylation states
|