SLAIN2 Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Required for normal structure of the microtubule cytoskeleton during interphase. Belongs to the SLAIN motif-containing family. Widely expressed with highest levels in adult liver, testis and ovary, and lowest levels in adult pancreas and spleen and in fetal brain. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of mouse Ortholog: 5|5 C3.2
Cellular Component:  centrosome; cytoplasm; cytoskeleton; cytosol; microtubule cytoskeleton; microtubule plus-end
Biological Process:  cytoplasmic microtubule organization; microtubule nucleation; positive regulation of microtubule polymerization; regulation of microtubule polymerization
Reference #:  Q8CI08 (UniProtKB)
Alt. Names/Synonyms: 5033405K12Rik; 8030444K12Rik; AI596370; Kiaa1458; MGC47019; mKIAA1458; SLAI2; SLAIN motif family, member 2; SLAIN motif-containing protein 2; Slain2
Gene Symbols: Slain2
Molecular weight: 62,378 Da
Basal Isoelectric point: 9.5  Predict pI for various phosphorylation states
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SLAIN2

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene