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SLAIN2
Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Required for normal structure of the microtubule cytoskeleton during interphase. Belongs to the SLAIN motif-containing family. Widely expressed with highest levels in adult liver, testis and ovary, and lowest levels in adult pancreas and spleen and in fetal brain. Note: This description may include information from UniProtKB.
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| Protein type: Unknown function |
| Chromosomal Location of human Ortholog: 4p11 |
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Cellular Component:
centrosome; cytosol; microtubule cytoskeleton; microtubule plus-end
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Molecular Function:
protein binding
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Biological Process:
cytoplasmic microtubule organization; microtubule nucleation; positive regulation of microtubule polymerization
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Reference #:
Q9P270
(UniProtKB)
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Alt. Names/Synonyms: FLJ21611; KIAA1458; SLAI2; SLAIN motif family member 2; SLAIN motif family, member 2; SLAIN motif-containing protein 2; SLAIN2
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Gene Symbols: SLAIN2
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Molecular weight:
62,543 Da
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Basal Isoelectric point:
9.48
Predict pI for various phosphorylation states
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