FASTKD1 Involved in the down-regulation of mitochondrial MT-ND3 mRNA levels which leads to decreased respiratory complex I abundance and activity. Belongs to the FAST kinase family. Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Apoptosis; RNA-binding
Chromosomal Location of human Ortholog: 2q31.1
Cellular Component:  mitochondrion
Molecular Function:  protein kinase activity
Biological Process:  cellular respiration; mitochondrial RNA metabolic process; protein phosphorylation; regulation of mitochondrial mRNA stability
Reference #:  Q53R41 (UniProtKB)
Alt. Names/Synonyms: FAKD1; FAST kinase domain-containing protein 1; FAST kinase domain-containing protein 1, mitochondrial; FAST kinase domains 1; FASTKD1; FLJ21901; KIAA1800
Gene Symbols: FASTKD1
Molecular weight: 97,411 Da
Basal Isoelectric point: 7.8  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene