ADAM18 Sperm surface membrane protein that may be involved in spermatogenesis and fertilization. This is a non catalytic metalloprotease-like protein. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Membrane protein, integral; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 8p11.22
Cellular Component:  integral component of membrane; membrane
Molecular Function:  metalloendopeptidase activity; metallopeptidase activity
Biological Process:  cell differentiation; multicellular organism development; proteolysis; spermatogenesis
Reference #:  Q9Y3Q7 (UniProtKB)
Alt. Names/Synonyms: a disintegrin and metalloproteinase domain 18; ADA18; ADAM 18; ADAM metallopeptidase domain 18; ADAM18; ADAM27; Disintegrin and metalloproteinase domain-containing protein 18; MGC41836; MGC88272; tMDC III; TMDC3; tMDCIII; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III
Gene Symbols: ADAM18
Molecular weight: 82,856 Da
Basal Isoelectric point: 7.16  Predict pI for various phosphorylation states
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ADAM18

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB