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syndecan-1
Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. Belongs to the syndecan proteoglycan family. Note: This description may include information from UniProtKB.
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| Protein type: Extracellular matrix; Membrane protein, integral; Motility/polarity/chemotaxis |
| Chromosomal Location of mouse Ortholog: 12 A1.1|12 3.94 cM |
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Cellular Component:
cell surface; external side of plasma membrane; extracellular region; Golgi lumen; membrane; plasma membrane; protein-containing complex
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Molecular Function:
cargo receptor activity; identical protein binding; protein binding
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Biological Process:
canonical Wnt signaling pathway; cell migration; myoblast development; positive regulation of exosomal secretion; positive regulation of extracellular exosome assembly; receptor-mediated endocytosis
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Reference #:
P18828
(UniProtKB)
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Alt. Names/Synonyms: AA408134; AA409076; CD138; Sdc1; Sstn; Syn; syn-1; Synd; Synd-1; SYND1; syndecan 1; Syndecan-1; synstatin
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Gene Symbols: Sdc1
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Molecular weight:
32,905 Da
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Basal Isoelectric point:
4.72
Predict pI for various phosphorylation states
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