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NPY4R
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PP, PP (2-36) and [Ile-31, Gln-34] PP Belongs to the G-protein coupled receptor 1 family. Highest levels found in brain, coronary artery and ileum. Low levels in pancreas and kidney. Detected in colon and small intestine. Note: This description may include information from UniProtKB.
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| Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR |
| Chromosomal Location of human Ortholog: 10q11.22 |
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Cellular Component:
integral component of plasma membrane; membrane; plasma membrane
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Molecular Function:
G protein-coupled receptor activity; pancreatic polypeptide receptor activity; peptide hormone binding
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Biological Process:
G protein-coupled receptor signaling pathway; neuropeptide signaling pathway
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Reference #:
P50391
(UniProtKB)
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Alt. Names/Synonyms: MGC116897; Neuropeptide Y receptor type 4; neuropeptide Y receptor Y4; NPY4-R; NPY4R; Pancreatic polypeptide receptor 1; PP1; PPYR1; Y4
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Gene Symbols: NPY4R
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Molecular weight:
42,142 Da
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Basal Isoelectric point:
8.29
Predict pI for various phosphorylation states
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