MYL6 Regulatory light chain of myosin. Does not bind calcium. 1 alternatively spliced human isoform has been reported. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis; Motor
Chromosomal Location of human Ortholog: 12q13.2
Cellular Component:  brush border; cytosol; myosin complex; myosin II complex; unconventional myosin complex
Molecular Function:  calcium ion binding; cytoskeletal motor activity; microfilament motor activity; protein binding; structural constituent of muscle
Biological Process:  muscle contraction; muscle filament sliding; skeletal muscle tissue development
Reference #:  P60660 (UniProtKB)
Alt. Names/Synonyms: 17 kDa myosin light chain; ESMLC; LC17; LC17-GI; LC17-NM; LC17A; LC17B; MLC-3; MLC1SM; MLC3NM; MLC3SM; MYL6; Myosin light chain 3; myosin light chain 6; Myosin light chain A3; Myosin light chain alkali 3; Myosin light polypeptide 6; myosin, light chain 6, alkali, smooth muscle and non-muscle; myosin, light polypeptide 6, alkali, smooth muscle and non-muscle; smooth muscle and non-muscle myosin alkali light chain; Smooth muscle and nonmuscle myosin light chain alkali 6
Gene Symbols: MYL6
Molecular weight: 16,930 Da
Basal Isoelectric point: 4.56  Predict pI for various phosphorylation states
CST Pathways:  Actin Dynamics
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein