HIVEP2 This protein specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, somatostatin receptor II, and interferon-beta genes. It may act in T-cell activation. Expressed in brain and skeletal muscle. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein; DNA-binding
Chromosomal Location of Human Ortholog: 6q24.2
Cellular Component:  nucleoplasm
Molecular Function:  DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; metal ion binding
Biological Process:  regulation of transcription by RNA polymerase II
Disease: Mental Retardation, Autosomal Dominant 43
Reference #:  P31629 (UniProtKB)
Alt. Names/Synonyms: c-myc intron binding protein 1; c-myc intron-binding protein 1; HIV-EP2; HIVEP zinc finger 2; HIVEP2; human immunodeficiency virus type I enhancer binding protein 2; Human immunodeficiency virus type I enhancer-binding protein 2; MBP-2; MHC binding protein-2; MHC-binding protein 2; MIBP1; MRD43; Schnurri-2; SHN2; Transcription factor HIVEP2; ZAS2; ZEP2; ZNF40B
Gene Symbols: HIVEP2
Molecular weight: 269,053 Da
Basal Isoelectric point: 6.5  Predict pI for various phosphorylation states
Select Structure to View Below

HIVEP2

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene