GPRC5C This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways. Belongs to the G-protein coupled receptor 3 family. Expression is highest in the periphery, particularly in the stomach, but also in the kidney, liver, pancreas, and prostate. In brain, levels of expression are generally lower than in the periphery, with the exception of cerebellum, spinal cord, and dorsal root ganglia (DRG). 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 3; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 11|11 E2
Cellular Component:  extracellular exosome; integral component of membrane; intracellular membrane-bounded organelle; membrane; plasma membrane; receptor complex
Molecular Function:  G protein-coupled receptor activity; protein kinase activator activity; sevenless binding
Biological Process:  G protein-coupled receptor signaling pathway; signal transduction; visual perception
Reference #:  Q8K3J9 (UniProtKB)
Alt. Names/Synonyms: 1110028I06Rik; 3200002M13Rik; G protein-coupled receptor, family C, group 5, member C; G-protein coupled receptor family C group 5 member C; GPC5C; Gprc5c; MGC11976; MGC6786; OTTMUSP00000003542; RAIG-3; Raig3; retinoic acid inducible protein 3; Retinoic acid-induced gene 3 protein
Gene Symbols: Gprc5c
Molecular weight: 48,422 Da
Basal Isoelectric point: 7.57  Predict pI for various phosphorylation states
Select Structure to View Below

GPRC5C

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene