GPRC5C
This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways. Belongs to the G-protein coupled receptor 3 family. Expression is highest in the periphery, particularly in the stomach, but also in the kidney, liver, pancreas, and prostate. In brain, levels of expression are generally lower than in the periphery, with the exception of cerebellum, spinal cord, and dorsal root ganglia (DRG). 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: GPCR, family 3; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR |
Chromosomal Location of mouse Ortholog: 11|11 E2 |
Cellular Component:
extracellular exosome; intracellular membrane-bounded organelle; membrane; plasma membrane; receptor complex
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Molecular Function:
G protein-coupled receptor activity; protein kinase activator activity; sevenless binding
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Biological Process:
G protein-coupled receptor signaling pathway; signal transduction; visual perception
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Reference #:
Q8K3J9
(UniProtKB)
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Alt. Names/Synonyms: 1110028I06Rik; 3200002M13Rik; G protein-coupled receptor, family C, group 5, member C; G-protein coupled receptor family C group 5 member C; GPC5C; Gprc5c; MGC11976; MGC6786; OTTMUSP00000003542; RAIG-3; Raig3; retinoic acid inducible protein 3; Retinoic acid-induced gene 3 protein
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Gene Symbols: Gprc5c
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Molecular weight:
48,422 Da
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Basal Isoelectric point:
7.57
Predict pI for various phosphorylation states
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