GIMAP1
May regulate lymphocyte survival. Required for normal levels of mature T-lymphocytes and mature B-cells. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. Predominantly expressed in the spleen and to a lesser extent in the lymph nodes. Detected in T-cells. Note: This description may include information from UniProtKB.
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Protein type: Endoplasmic reticulum; Hydrolase; Membrane protein, integral |
Chromosomal Location of human Ortholog: 7q36.1 |
Cellular Component:
endoplasmic reticulum; endoplasmic reticulum membrane; Golgi membrane
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Molecular Function:
GTP binding; protein binding
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Reference #:
Q8WWP7
(UniProtKB)
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Alt. Names/Synonyms: GIMA1; GIMAP1; GTPase IMAP family member 1; GTPase, IMAP family member 1; hIMAP1; IAN2; IMAP1; IMAP38; immune-associated nucleotide-binding protein 2; immunity associated protein 1; Immunity-associated protein 1
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Gene Symbols: GIMAP1
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Molecular weight:
34,369 Da
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Basal Isoelectric point:
9.11
Predict pI for various phosphorylation states
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