GIMAP1 May regulate lymphocyte survival. Required for normal levels of mature T-lymphocytes and mature B-cells. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. Predominantly expressed in the spleen and to a lesser extent in the lymph nodes. Detected in T-cells. Note: This description may include information from UniProtKB.
Protein type: Endoplasmic reticulum; Hydrolase; Membrane protein, integral
Chromosomal Location of human Ortholog: 7q36.1
Cellular Component:  endoplasmic reticulum; endoplasmic reticulum membrane; Golgi membrane
Molecular Function:  GTP binding; protein binding
Reference #:  Q8WWP7 (UniProtKB)
Alt. Names/Synonyms: GIMA1; GIMAP1; GTPase IMAP family member 1; GTPase, IMAP family member 1; hIMAP1; IAN2; IMAP1; IMAP38; immune-associated nucleotide-binding protein 2; immunity associated protein 1; Immunity-associated protein 1
Gene Symbols: GIMAP1
Molecular weight: 34,369 Da
Basal Isoelectric point: 9.11  Predict pI for various phosphorylation states
Select Structure to View Below

GIMAP1

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein