BHMT Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline. Found exclusively in liver and kidney. Note: This description may include information from UniProtKB.
Protein type: Amino Acid Metabolism - cysteine and methionine; Amino Acid Metabolism - glycine, serine and threonine; EC; Methyltransferase
Chromosomal Location of Human Ortholog: 13|13 C3
Cellular Component:  cytosol; extracellular exosome; protein-containing complex
Molecular Function:  betaine-homocysteine S-methyltransferase activity; methyltransferase activity; protein-containing complex binding; zinc ion binding
Biological Process:  amino-acid betaine metabolic process; L-methionine salvage; methionine biosynthetic process; protein methylation
Reference #:  O35490 (UniProtKB)
Alt. Names/Synonyms: Betaine--homocysteine S-methyltransferase 1; betaine-homocysteine methyltransferase; Bhmt; BHMT1; MGC117976; MGC46866; OTTMUSP00000029215
Gene Symbols: Bhmt
Molecular weight: 45,021 Da
Basal Isoelectric point: 8.01  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene