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BHMT
Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline. Found exclusively in liver and kidney. Note: This description may include information from UniProtKB.
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| Protein type: Amino Acid Metabolism - cysteine and methionine; Amino Acid Metabolism - glycine, serine and threonine; EC 2.1.1.5; Methyltransferase |
| Chromosomal Location of Human Ortholog: 13|13 C3 |
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Cellular Component:
cytosol; extracellular exosome; protein-containing complex
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Molecular Function:
betaine-homocysteine S-methyltransferase activity; methyltransferase activity; protein-containing complex binding; zinc ion binding
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Biological Process:
amino-acid betaine metabolic process; L-methionine salvage; methionine biosynthetic process; protein methylation
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Reference #:
O35490
(UniProtKB)
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Alt. Names/Synonyms: Betaine--homocysteine S-methyltransferase 1; betaine-homocysteine methyltransferase; Bhmt; BHMT1; MGC117976; MGC46866; OTTMUSP00000029215
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Gene Symbols: Bhmt
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Molecular weight:
45,021 Da
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Basal Isoelectric point:
8.01
Predict pI for various phosphorylation states
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