BHMT Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline. Note: This description may include information from UniProtKB.
Protein type: Amino Acid Metabolism - cysteine and methionine; Amino Acid Metabolism - glycine, serine and threonine; EC 2.1.1.5; Methyltransferase
Chromosomal Location of Human Ortholog: 5q14.1
Cellular Component:  cytosol; extracellular exosome
Molecular Function:  betaine-homocysteine S-methyltransferase activity; zinc ion binding
Biological Process:  amino-acid betaine catabolic process; amino-acid betaine metabolic process; choline catabolic process; L-methionine salvage; protein methylation; regulation of homocysteine metabolic process; sulfur amino acid metabolic process
Reference #:  Q93088 (UniProtKB)
Alt. Names/Synonyms: betaine homocysteine methyltransferase; Betaine--homocysteine S-methyltransferase 1; betaine-homocysteine methyltransferase; BHMT; BHMT1
Gene Symbols: BHMT
Molecular weight: 44,998 Da
Basal Isoelectric point: 6.58  Predict pI for various phosphorylation states
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BHMT

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene