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BHMT
Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline. Note: This description may include information from UniProtKB.
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| Protein type: Amino Acid Metabolism - cysteine and methionine; Amino Acid Metabolism - glycine, serine and threonine; EC 2.1.1.5; Methyltransferase |
| Chromosomal Location of Human Ortholog: 5q14.1 |
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Cellular Component:
cytosol; extracellular exosome
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Molecular Function:
betaine-homocysteine S-methyltransferase activity; zinc ion binding
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Biological Process:
amino-acid betaine catabolic process; amino-acid betaine metabolic process; choline catabolic process; L-methionine salvage; protein methylation; regulation of homocysteine metabolic process; sulfur amino acid metabolic process
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Reference #:
Q93088
(UniProtKB)
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Alt. Names/Synonyms: betaine homocysteine methyltransferase; Betaine--homocysteine S-methyltransferase 1; betaine-homocysteine methyltransferase; BHMT; BHMT1
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Gene Symbols: BHMT
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Molecular weight:
44,998 Da
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Basal Isoelectric point:
6.58
Predict pI for various phosphorylation states
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