AUP1 May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome. Belongs to the AUP1 family. Detected in blood platelets and leukocytes (at protein level). Ubiquitous. Highly expressed in placenta, liver, kidney, skeletal muscle, heart and brain. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Endoplasmic reticulum; Membrane protein, integral; Transferase
Chromosomal Location of Human Ortholog: 2p13.1
Cellular Component: 
Molecular Function:  protein binding
Biological Process:  regulation of catalytic activity; retrograde protein transport, ER to cytosol
Reference #:  Q9Y679 (UniProtKB)
Alt. Names/Synonyms: Ancient ubiquitous protein 1; AUP1; AUP1 lipid droplet regulating VLDL assembly factor
Gene Symbols: AUP1
Molecular weight: 45,787 Da
Basal Isoelectric point: 8.96  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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AUP1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene