ARF5 GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. (Microbial infection) Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Belongs to the small GTPase superfamily. Arf family. Note: This description may include information from UniProtKB.
Protein type: G protein; G protein, monomeric; G protein, monomeric, ARF; Motility/polarity/chemotaxis
Chromosomal Location of mouse Ortholog: 6|6 A3.3
Cellular Component:  cytoplasm; Golgi apparatus; membrane; plasma membrane
Molecular Function:  GTP binding; GTPase activity; nucleotide binding; protein binding
Biological Process:  intracellular protein transport; protein transport; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; vesicle-mediated transport
Reference #:  P84084 (UniProtKB)
Alt. Names/Synonyms: ADP-ribosylation factor 5; Arf5; OTTMUSP00000023551
Gene Symbols: Arf5
Molecular weight: 20,530 Da
Basal Isoelectric point: 6.3  Predict pI for various phosphorylation states
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ARF5

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein