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ARF5
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. (Microbial infection) Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Belongs to the small GTPase superfamily. Arf family. Note: This description may include information from UniProtKB.
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| Protein type: G protein; G protein, monomeric; G protein, monomeric, ARF; Motility/polarity/chemotaxis |
| Chromosomal Location of Human Ortholog: 7q32.1 |
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Cellular Component:
perinuclear region of cytoplasm
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Molecular Function:
GTPase activity; protein binding
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Biological Process:
retrograde vesicle-mediated transport, Golgi to ER
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Reference #:
P84085
(UniProtKB)
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Alt. Names/Synonyms: ADP ribosylation factor 5; ADP-ribosylation factor 5; ARF5
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Gene Symbols: ARF5
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Molecular weight:
20,530 Da
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Basal Isoelectric point:
6.3
Predict pI for various phosphorylation states
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