ARF3 GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family. Note: This description may include information from UniProtKB.
Protein type: G protein; G protein, monomeric; G protein, monomeric, ARF; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 15|15 F1
Cellular Component:  cytoplasm; Golgi apparatus; plasma membrane
Molecular Function:  GTP binding; nucleotide binding
Biological Process:  Golgi to plasma membrane transport; intracellular protein transport; protein transport; retrograde vesicle-mediated transport, Golgi to ER; vesicle-mediated transport
Reference #:  P61205 (UniProtKB)
Alt. Names/Synonyms: 5430400P17Rik; ADP-ribosylation factor 3; AI854770; Arf3; OTTMUSP00000018494
Gene Symbols: Arf3
Molecular weight: 20,601 Da
Basal Isoelectric point: 6.84  Predict pI for various phosphorylation states
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ARF3

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene