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ARF3
GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: G protein; G protein, monomeric; G protein, monomeric, ARF; Motility/polarity/chemotaxis |
| Chromosomal Location of mouse Ortholog: 15|15 F1 |
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Cellular Component:
cytoplasm; Golgi apparatus; plasma membrane
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Molecular Function:
GTP binding; GTPase activity; nucleotide binding
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Biological Process:
intracellular protein transport; protein transport; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; vesicle-mediated transport
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Reference #:
P61205
(UniProtKB)
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Alt. Names/Synonyms: 5430400P17Rik; ADP-ribosylation factor 3; AI854770; Arf3; OTTMUSP00000018494
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Gene Symbols: Arf3
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Molecular weight:
20,601 Da
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Basal Isoelectric point:
6.84
Predict pI for various phosphorylation states
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