14-3-3 gamma Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Belongs to the 14-3-3 family. Highly expressed in brain, skeletal muscle, and heart. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold
Chromosomal Location of mouse Ortholog: 5|5 G2
Cellular Component:  cytoplasm; cytosol; presynapse; synapse; vesicle
Molecular Function:  identical protein binding; insulin-like growth factor receptor binding; protein binding; protein domain specific binding; protein kinase C binding; receptor tyrosine kinase binding
Biological Process:  cellular response to insulin stimulus; protein localization; protein targeting; regulation of neuron differentiation; regulation of synaptic plasticity; signal transduction
Reference #:  P61982 (UniProtKB)
Alt. Names/Synonyms: 14-3-3 gamma; 14-3-3 protein gamma; 14-3-3 protein gamma subtype; 14-3-3 protein gamma, N-terminally processed; 14-3-3gamma; 1433G; 3-monooxgenase/tryptophan 5-monooxgenase activation protein, gamma polypeptide; 3-monooxgenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; D7Bwg1348e; OTTMUSP00000017492; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; Ywhag
Gene Symbols: Ywhag
Molecular weight: 28,303 Da
Basal Isoelectric point: 4.8  Predict pI for various phosphorylation states
CST Pathways:  Apoptosis Regulation  |  G2/M DNA Damage Checkpoint  |  Growth And Differentiation Control by MAPKs  |  Mitochondrial Control of Apoptosis  |  PI3K/Akt Signaling
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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14-3-3 gamma

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene