CK1G1 Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate. Phosphorylates CLSPN. Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: CK1 group; CK1 family; CK1-G subfamily; EC 2.7.11.1; Kinase, protein; Protein kinase, CK1; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of human Ortholog: 15q22.31
Cellular Component:  cytoplasm; cytosol; nucleus; plasma membrane
Molecular Function:  ATP binding; protein binding; protein serine kinase activity; protein serine/threonine kinase activity
Biological Process:  endocytosis; peptidyl-serine phosphorylation; positive regulation of canonical Wnt signaling pathway; signal transduction; Wnt signaling pathway
Reference #:  Q9HCP0 (UniProtKB)
Alt. Names/Synonyms: casein kinase 1 gamma 1; casein kinase 1, gamma 1; Casein kinase I isoform gamma-1; CK1G1; CK1gamma1; CKI-gamma 1; CSNK1G1; KC1G1
Gene Symbols: CSNK1G1
Molecular weight: 48,511 Da
Basal Isoelectric point: 9.13  Predict pI for various phosphorylation states
CST Pathways:  Hedgehog Signaling  |  Wnt/ß-Catenin Signaling
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CK1G1

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  KinBase  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein