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liprin beta 1 iso2
May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A. Belongs to the liprin family. Liprin-beta subfamily. Widely expressed. Absent in liver. 5 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Adaptor/scaffold |
| Chromosomal Location of human Ortholog: 12p11.23-p11.22 |
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Cellular Component:
cytosol; plasma membrane; presynaptic active zone
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Molecular Function:
protein binding
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Biological Process:
cell adhesion; neuromuscular junction development
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Disease: Neurodevelopmental Disorder With Seizures, Microcephaly, And Brain Abnormalities
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Reference #:
Q86W92-2
(UniProtKB)
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Alt. Names/Synonyms: hSGT2; hSgt2p; KIAA1230; L2; LIPB1; liprin beta 1 iso2; liprin related protein; liprin-beta 1; Liprin-beta-1; PPFIA binding protein 1; PPFIBP1; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1; protein-tyrosine phosphatase receptor-type f polypeptide-interacting protein-binding protein 1; PTPRF interacting protein, binding protein 1 (liprin beta 1); PTPRF-interacting protein-binding protein 1; SGT2
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Gene Symbols: PPFIBP1
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Molecular weight:
113,181 Da
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Basal Isoelectric point:
5.49
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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