epsin 2 iso2 Plays a role in the formation of clathrin-coated invaginations and endocytosis. Belongs to the epsin family. Highest expression is found in brain. Detected at lower levels in lung and liver. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 17p11.2
Cellular Component:  clathrin coat of endocytic vesicle; cytosol; intracellular membrane-bounded organelle
Molecular Function:  lipid binding; protein binding
Biological Process:  endocytosis; membrane organization; negative regulation of sprouting angiogenesis; negative regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of Notch signaling pathway
Reference #:  O95208-2 (UniProtKB)
Alt. Names/Synonyms: EHB21; EPN2; EPS-15-interacting protein 2; Eps15 binding protein; epsin 2; epsin 2 iso2; Epsin-2; KIAA1065
Gene Symbols: EPN2
Molecular weight: 62,300 Da
Basal Isoelectric point: Predict pI for various phosphorylation states
CST Pathways:  Notch Signaling
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epsin 2 iso2

Protein Structure Not Found.

Cross-references to other databases:  cBioPortal  |  Wikipedia  |  Pfam  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein