PSMD13 Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. Belongs to the proteasome subunit S11 family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Protease; Proteasome complex
Chromosomal Location of rat Ortholog: 1q41
Cellular Component:  cytosol; nucleus; proteasome accessory complex; proteasome complex; proteasome regulatory particle; proteasome regulatory particle, lid subcomplex
Molecular Function:  structural molecule activity
Biological Process:  meiosis I; proteasome assembly; ubiquitin-dependent protein catabolic process
Reference #:  B0BN93 (UniProtKB)
Alt. Names/Synonyms: 26S proteasome non-ATPase regulatory subunit 13; 26S proteasome regulatory subunit p40.5; 26S proteasome regulatory subunit S11; proteasome (prosome, macropain) 26S subunit, non-ATPase, 13; PSD13; Psmd13
Gene Symbols: Psmd13
Molecular weight: 42,817 Da
Basal Isoelectric point: 5.55  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene