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GDA
Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: EC 3.5.4.3; Hydrolase; Nucleotide Metabolism - purine |
| Chromosomal Location of rat Ortholog: 1q51 |
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Cellular Component:
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Molecular Function:
guanine deaminase activity; zinc ion binding
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Biological Process:
guanine catabolic process; guanine metabolic process; positive regulation of microtubule polymerization
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Reference #:
Q9WTT6
(UniProtKB)
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Alt. Names/Synonyms: Cypin; GAH; Gda; GUAD; Guanase; Guanine aminase; Guanine aminohydrolase; Guanine deaminase
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Gene Symbols: Gda
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Molecular weight:
51,016 Da
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Basal Isoelectric point:
5.56
Predict pI for various phosphorylation states
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