GDA Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC 3.5.4.3; Hydrolase; Nucleotide Metabolism - purine
Chromosomal Location of rat Ortholog: 1q51
Cellular Component: 
Molecular Function:  guanine deaminase activity; zinc ion binding
Biological Process:  guanine catabolic process; guanine metabolic process; positive regulation of microtubule polymerization
Reference #:  Q9WTT6 (UniProtKB)
Alt. Names/Synonyms: Cypin; GAH; Gda; GUAD; Guanase; Guanine aminase; Guanine aminohydrolase; Guanine deaminase
Gene Symbols: Gda
Molecular weight: 51,016 Da
Basal Isoelectric point: 5.56  Predict pI for various phosphorylation states
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GDA

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene