HDGF2 iso3 Involved in cellular growth control, through the regulation of cyclin D1 expression. Belongs to the HDGF family. Widely expressed. High expression is found in heart, skeletal muscle, ovary and testis. Overexpression is frequently observed in hepatocellular carcinoma samples. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Chromosomal Location of Human Ortholog: 17|17 D
Cellular Component:  nucleus
Molecular Function:  chromatin binding; protein binding
Biological Process:  positive regulation of cell growth
Reference #:  Q3UMU9-3 (UniProtKB)
Alt. Names/Synonyms: HDGF like 2; Hdgfl2; Hdgfrp2; HDGR2; hepatoma-derived growth factor, related protein 2; Hepatoma-derived growth factor-related protein 2; HRP-2
Gene Symbols: Hdgfl2
Molecular weight: 75,246 Da
Basal Isoelectric point: 8.68  Predict pI for various phosphorylation states
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HDGF2 iso3

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene