CFP A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Note: This description may include information from UniProtKB.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of human Ortholog: Xp11.23
Cellular Component:  endoplasmic reticulum lumen; extracellular region; extracellular space; plasma membrane; specific granule lumen; tertiary granule lumen
Molecular Function:  protein binding
Biological Process:  complement activation; complement activation, alternative pathway; defense response to bacterium; immune response; positive regulation of immune response; positive regulation of opsonization
Disease: Properdin Deficiency, X-linked
Reference #:  P27918 (UniProtKB)
Alt. Names/Synonyms: BFD; CFP; Complement factor P; complement factor properdin; PFC; PFD; PROP; Properdin; properdin P factor, complement
Gene Symbols: CFP
Molecular weight: 51,276 Da
Basal Isoelectric point: 8.32  Predict pI for various phosphorylation states
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CFP

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene