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CFP
A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Note: This description may include information from UniProtKB.
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| Protein type: Secreted; Secreted, signal peptide |
| Chromosomal Location of human Ortholog: Xp11.23 |
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Cellular Component:
endoplasmic reticulum lumen; extracellular region; extracellular space; plasma membrane; specific granule lumen; tertiary granule lumen
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Molecular Function:
protein binding
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Biological Process:
complement activation; complement activation, alternative pathway; defense response to bacterium; immune response; positive regulation of immune response; positive regulation of opsonization
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Disease: Properdin Deficiency, X-linked
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Reference #:
P27918
(UniProtKB)
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Alt. Names/Synonyms: BFD; CFP; Complement factor P; complement factor properdin; PFC; PFD; PROP; Properdin; properdin P factor, complement
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Gene Symbols: CFP
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Molecular weight:
51,276 Da
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Basal Isoelectric point:
8.32
Predict pI for various phosphorylation states
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