CFP
A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Note: This description may include information from UniProtKB.
Protein type: Secreted; Secreted, signal peptideChromosomal Location of mouse Ortholog: X A1.3|X 16.44 cM
Cellular Component:
extracellular region; extracellular space; plasma membrane; secretory granule
Biological Process:
complement activation; complement activation, alternative pathway; immune system process; innate immune response; positive regulation of immune response; positive regulation of opsonization
Reference #:
P11680
(UniProtKB)
Alt. Names/Synonyms: BCFG; Cfp; Complement factor P; complement factor properdin; OTTMUSP00000018689; Pfc; PROP; Properdin; properdin factor, complement
Gene Symbols: Cfp
Molecular weight:
50,327 Da
Basal Isoelectric point:
8.25
Predict pI for various phosphorylation states
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CFP
1W0R - A/B=28-469 (human)
1W0S - A/C/B=28-469 (human)
6RUR - A/G=23-667 H/B=749-1663 (human)
6RUS - A=28-255 B=256-469 (human)
6RUV - A/G=23-667 H/B=749-1663 (human)
6RV6 - A=28-191 B=256-469 (human)
6S08 - A=256-469 B=26-132 (human)
6S0A - A=256-469 B=26-191 (human)
6S0B - C=1517-1663 (human)
6SEJ - A=28-191 B=256-469 (human)
7B26 - A=1-134, B=256-469 (human)
7NOZ - C=28-190, D=255-461 (human)
